Highly elastomeric poly(glycerol sebacate)-co-poly(ethylene glycol) amphiphilic block copolymers.

@article{Patel2013HighlyEP,
  title={Highly elastomeric poly(glycerol sebacate)-co-poly(ethylene glycol) amphiphilic block copolymers.},
  author={Alpesh Patel and Akhilesh K Gaharwar and Giorgio Iviglia and Hongbin Zhang and Shilpaa Mukundan and Silvia M. Mihaila and Danilo Demarchi and Ali Khademhosseini},
  journal={Biomaterials},
  year={2013},
  volume={34 16},
  pages={3970-3983}
}
Poly(glycerol sebacate) (PGS), a tough elastomer, has been proposed for tissue engineering applications due to its desired mechanical properties, biocompatibility and controlled degradation. Despite interesting physical and chemical properties, PGS shows limited water uptake capacity (∼2%), thus constraining its utility for soft tissue engineering. Therefore, a modification of PGS that would mimic the water uptake and water retention characteristics of natural extracellular matrix is beneficial… CONTINUE READING
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