Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions

@article{Cao2013HighlyEI,
  title={Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions},
  author={Nan Cao and He Yue Liang and Jijun Huang and Jia Wang and Yixiong Chen and Zhongyan Chen and Huang-Tian Yang},
  journal={Cell Research},
  year={2013},
  volume={23},
  pages={1119-1132}
}
Cardiovascular progenitor cells (CVPCs) derived from human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), hold great promise for the study of cardiovascular development and cell-based therapy of heart diseases, but their applications are challenged by the difficulties in their efficient generation and stable maintenance. This study aims to develop chemically defined systems for robust generation and stable… CONTINUE READING
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