Highly effective phosphorylation by G protein-coupled receptor kinase 7 of light-activated visual pigment in cones.

@article{Tachibanaki2005HighlyEP,
  title={Highly effective phosphorylation by G protein-coupled receptor kinase 7 of light-activated visual pigment in cones.},
  author={Shuji Tachibanaki and Daisuke Arinobu and Yoshie Shimauchi-Matsukawa and Sawae Tsushima and Satoru Kawamura},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2005},
  volume={102 26},
  pages={9329-34}
}
Cone photoreceptors show briefer photoresponses than rod photoreceptors. Our previous study showed that visual pigment phosphorylation, a quenching mechanism of light-activated visual pigment, is much more rapid in cones than in rods. Here, we measured the early time course of this rapid phosphorylation with good time resolution and directly compared it with the photoresponse time course in cones. At the time of photoresponse recovery, almost two phosphates were incorporated into a bleached… CONTINUE READING

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