Highly effective generic adjuvant systems for orphan or poverty-related vaccines.

@article{Rao2011HighlyEG,
  title={Highly effective generic adjuvant systems for orphan or poverty-related vaccines.},
  author={M. Rao and K. Peachman and Qin Li and G. Matyas and S. B. Shivachandra and R. Borschel and V. Morthole and C. Fernandez-Prada and C. Alving and V. Rao},
  journal={Vaccine},
  year={2011},
  volume={29 5},
  pages={
          873-7
        }
}
Safe and effective adjuvants are needed for many vaccines with limited commercial appeal, such as vaccines to infrequent (orphan) diseases or to neglected and poverty-related diseases. Here we found that three nonproprietary liposome formulations containing monophosphoryl lipid A each induced 3-fold to 5-fold increased titers of binding and neutralizing antibodies to anthrax protective antigen compared to aluminum hydroxide-adsorbed antigen in monkeys. All vaccinated monkeys were protected… Expand
Adjuvants for human vaccines.
Prophylactic vaccine delivery systems against epidemic infectious diseases
Selection of Adjuvants for Enhanced Vaccine Potency
Army Liposome Formulation (ALF) family of vaccine adjuvants
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