Highly abnormal thermotests in familial dysautonomia suggest increased cardiac autonomic risk.

@article{Hilz1998HighlyAT,
  title={Highly abnormal thermotests in familial dysautonomia suggest increased cardiac autonomic risk.},
  author={Max J Hilz and Edwin H. Kolodny and Irene Neuner and Brigitte Stemper and Felicia B. Axelrod},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={1998},
  volume={65 3},
  pages={338-43}
}
OBJECTIVE Patients with familial dysautonomia have an increased risk of sudden death. In some patients with familial dysautonomia, sympathetic cardiac dysfunction is indicated by prolongation of corrected QT (QTc) interval, especially during stress tests. As many patients do not tolerate physical stress, additional indices are needed to predict autonomic risk. In familial dysautonomia there is a reduction of both sympathetic neurons and peripheral small nerve fibres which mediate temperature… CONTINUE READING
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