Highly Sensitive to Their Regression Provides an Accurate Measure of Atherosclerotic Lesions Rich in Oxidized LDL and Is In Vivo Uptake of Radiolabeled MDA2, an Oxidation-Specific Monoclonal Antibody,

Abstract

To determine whether labeled antibodies against oxidized LDL (OxLDL) offer advantages for quantifying atherosclerosis, we compared in vivo aortic uptake of I-labeled MDA2, a monoclonal antibody against malondialdehyde-lysine epitopes), atherosclerotic surface area, and aortic weight in Watanabe heritable hyperlipidemic and New Zealand White rabbits and in… (More)

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