Highly Diastereoselective Route to α-Glucosidase Inhibitors, Neosalacinol and Neoponkoranol.

@article{Tanabe2016HighlyDR,
  title={Highly Diastereoselective Route to α-Glucosidase Inhibitors, Neosalacinol and Neoponkoranol.},
  author={G. Tanabe and Youya Matsuda and Misato Oka and Yousuke Kunikata and N. Tsutsui and Weija Xie and G. Balakishan and Mumen F. A. Amer and Shinsuke Marumoto and O. Muraoka},
  journal={The Journal of organic chemistry},
  year={2016},
  volume={81 8},
  pages={
          3407-15
        }
}
  • G. Tanabe, Youya Matsuda, +7 authors O. Muraoka
  • Published 2016
  • Chemistry, Medicine
  • The Journal of organic chemistry
  • A facile and highly diastereoselective route to potent natural α-glucosidase inhibitors, i.e., neosalacinol (4) and neoponkoranol (6), isolated from the traditional Ayurvedic medicine "Salacia" was developed by intramolecular cyclization of appropriately substituted sulfides (9 and 12). 
    4 Citations

    Figures and Topics from this paper

    Explore Further: Topics Discussed in This Paper

    References

    SHOWING 1-10 OF 28 REFERENCES
    A new class of glycosidase inhibitor: synthesis of salacinol and its stereoisomers.
    • 81
    Alpha-glucosidase inhibitor from Kothala-himbutu (Salacia reticulata WIGHT).
    • 43