Highlights in basic autonomic neurosciences: Remote ischaemic preconditioning as an autonomic reflex — A question of timing and circumstances?

@article{Ang2013HighlightsIB,
  title={Highlights in basic autonomic neurosciences: Remote ischaemic preconditioning as an autonomic reflex — A question of timing and circumstances?},
  author={Richard Ang},
  journal={Autonomic Neuroscience},
  year={2013},
  volume={173},
  pages={1-2}
}
Myocardial ischaemia–reperfusion injury was induced in pentobarbital anaesthetised rats by ligating the left anterior descending (LAD) coronary artery for 30 min followed by 60 min of reperfusion. Remote ischaemic conditioning (RIc) was performed by temporary bilateral occlusion of femoral arteries for 15 min. The investigators found a reduction in infarct size by about 50% when RIc stimulus was applied 25 min prior to myocardial ischaemia, 10 or 25 min after the onset of ischaemia and 10 min… CONTINUE READING