Higher serum DHEA concentrations before and after SSRI treatment are associated with remission of major depression.

Abstract

BACKGROUND Dehydroepiandrosterone (DHEA) and its sulfated ester DHEA-sulfate (DHEA-S), (together DHEA[S]), are the most abundant adrenal steroids in humans and are found in blood and the brain, where they function as neurosteroids with direct receptor affinities. Preclinical studies suggest that DHEA(S) has antidepressant/neuroprotective properties, and… (More)
DOI: 10.1016/j.psyneuen.2016.11.035

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Cite this paper

@article{Hough2017HigherSD, title={Higher serum DHEA concentrations before and after SSRI treatment are associated with remission of major depression.}, author={Christina M. Hough and Daniel Lindqvist and Elissa S Epel and Molly St Denis and Victor I. Reus and Francesco Saverio Bersani and Rebecca L Rosser and L. Kathleen Mahan and Heather M. Burke and Owen M. Wolkowitz and Synthia H. Mellon}, journal={Psychoneuroendocrinology}, year={2017}, volume={77}, pages={122-130} }