Higher rates of decline for women and apolipoprotein E epsilon4 carriers.


BACKGROUND AND PURPOSE Age and the apolipoprotein E ε4 allele are well-known risk factors for Alzheimer disease, but whether female sex is also a risk factor remains controversial. It is also unclear how these risk factors affect rates of structural brain and clinical decline across the spectrum of preclinical to clinical Alzheimer disease. Our objective is… (More)
DOI: 10.3174/ajnr.A3601



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