Higher-order orchestration of hematopoiesis: is cohesin a new player?

  title={Higher-order orchestration of hematopoiesis: is cohesin a new player?},
  author={Anil Kumar Panigrahi and Debananda Pati},
  journal={Experimental hematology},
  volume={40 12},
Hematopoiesis-the process that generates distinct lineage-committed blood cells from a single multipotent hematopoietic stem cell-is a complex process of cellular differentiation regulated by a set of dynamic transcriptional programs. Cytokines and growth factors, transcription factors, chromatin remodeling, and modifying enzymes have been suggested to enact critical roles during hematopoiesis, leading to the development of myeloid, lymphoid, erythroid and platelet precursors. How is such a… CONTINUE READING
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