Higher order inclusion complexes and secondary interactions studied by global analysis of calorimetric titrations.

@article{Schnbeck2012HigherOI,
  title={Higher order inclusion complexes and secondary interactions studied by global analysis of calorimetric titrations.},
  author={Christian Sch{\"o}nbeck and Ren{\'e} Holm and Peter Westh},
  journal={Analytical chemistry},
  year={2012},
  volume={84 5},
  pages={2305-12}
}
This paper investigates the use of isothermal titration calorimetry (ITC) as a tool for studying molecular systems in which weaker secondary interactions are present in addition to a dominant primary interaction. Such systems are challenging since the signal pertaining to the stronger primary interaction tends to overshadow the signal from the secondary interaction. The methodology presented here enables a complete and precise thermodynamic characterization of both the primary and the weaker… CONTINUE READING