Higher mRNA levels of chemokines and cytokines associated with macrophage activation in erythema migrans skin lesions in patients from the United States than in patients from Austria with Lyme borreliosis.

@article{Jones2008HigherML,
  title={Higher mRNA levels of chemokines and cytokines associated with macrophage activation in erythema migrans skin lesions in patients from the United States than in patients from Austria with Lyme borreliosis.},
  author={Kathryn L Jones and Robert R Muellegger and Terry K. Means and Marshall M C Lee and Lisa J. Glickstein and Nitin K. Damle and Vijay K Sikand and Andrew D Luster and Allen C. Steere},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2008},
  volume={46 1},
  pages={85-92}
}
BACKGROUND Erythema migrans (EM) is caused primarily by Borrelia afzelii in Europe and solely by Borrelia burgdorferi in the United States. B. burgdorferi infection in the United States has previously been associated with faster expansion of EM lesions and with more associated symptoms, compared with B. afzelii infection in Europe. However, reasons for these differences are not yet known. METHODS We determined the Borrelia species infecting 67 US or Austrian patients with EM. The clinical… CONTINUE READING
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