Higher levels of nicotine in arterial than in venous blood after cigarette smoking.

@article{Henningfield1993HigherLO,
  title={Higher levels of nicotine in arterial than in venous blood after cigarette smoking.},
  author={Jack E. Henningfield and June M. Stapleton and Neal L. Benowitz and Revonda Grayson and Edythe D. London},
  journal={Drug and alcohol dependence},
  year={1993},
  volume={33 1},
  pages={23-9}
}
We examined differences between arterial and venous concentrations of nicotine in human subjects. Shortly after smoking a cigarette, levels of nicotine in arterial plasma were more than double those in venous plasma. The time course of the rise in arterial nicotine levels and the magnitude of the arteriovenous difference varied considerably among subjects. For some subjects, arterial nicotine concentrations after one cigarette were similar to venous concentrations typically observed after 20… CONTINUE READING
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