Higher levels of dengue-virus-specific IgG and IgA during pre-defervescence associated with primary dengue hemorrhagic fever

@article{Bachal2015HigherLO,
  title={Higher levels of dengue-virus-specific IgG and IgA during pre-defervescence associated with primary dengue hemorrhagic fever},
  author={Rupali V Bachal and K Alagarasu and Anand Singh and Asha Salunke and Paresh Shah and Dayaraj Cecilia},
  journal={Archives of Virology},
  year={2015},
  volume={160},
  pages={2435-2443}
}
Dengue hemorrhagic fever (DHF), although predominantly associated with secondary infections, has also been reported in primary infections. An enhanced immune response including antibodies and cytokines is implicated in the pathogenesis of secondary DHF. However, the factors operating in primary DHF are poorly understood. To understand the role of the antibody response, the relative levels of different antibody isotypes during the acute phase of infection in primary and secondary dengue… CONTINUE READING
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