Higher insulin and glucagon-like peptide-1 (GLP-1) levels in healthy, young South Asians as compared to Caucasians during an oral glucose tolerance test.

@article{Sleddering2014HigherIA,
  title={Higher insulin and glucagon-like peptide-1 (GLP-1) levels in healthy, young South Asians as compared to Caucasians during an oral glucose tolerance test.},
  author={Maria Alexandra Sleddering and Leontine E. H. Bakker and Laura G. M. Janssen and Arend Edo Meinders and Ingrid M. Jazet},
  journal={Metabolism: clinical and experimental},
  year={2014},
  volume={63 2},
  pages={226-32}
}
OBJECTIVE Higher insulin levels during an oral glucose test (OGTT) have been shown in South Asians. We aimed to investigate if this increased insulin response causes reactive hypoglycemia later on, and if an increased glucagon-like-peptide-1 (GLP-1) response, which could contribute to the hyperinsulinemia, is present in this ethnic group. METHODS A prolonged, 6-h, 75-g OGTT was performed in healthy, young Caucasian (n=10) and South Asian (n=8) men. The glucose, insulin and GLP-1 response was… CONTINUE READING
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