Higher incidence of autoantibodies in X-linked chronic granulomatous disease carriers: random X-chromosome inactivation may be related to autoimmunity.

Abstract

The presence of autoantibodies and autoimmune diseases was tested in all available members of five families with at least one member affected with X-linked chronic granulomatous disease. Patients and carriers relatives possess autoantibodies more frequently than non-carriers relatives (95% vs 10%, p < 1.0 x 10(-5), Fisher test). Further, a survey of the… (More)

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Cite this paper

@article{MartnVilla1999HigherIO, title={Higher incidence of autoantibodies in X-linked chronic granulomatous disease carriers: random X-chromosome inactivation may be related to autoimmunity.}, author={Jos{\'e} Manuel Mart{\'i}n-Villa and Alfredo Corell and Jos{\'e} Tom{\'a}s Ramos-Amador and J{\'e}sus Ruiz-Contreras and Antonio Arnaiz-Villena}, journal={Autoimmunity}, year={1999}, volume={31 4}, pages={261-4} }