Higher expression levels of 14-3-3sigma in ductal carcinoma in situ of the breast predict poorer outcome.

Abstract

The protein 14-3-3sigma is involved in the regulation of cellular processes such as apoptosis, cell cycle progression and proliferation. Disruption of protein expression has been implicated in a number of malignancies. Here we examine the expression pattern of 14-3-3sigma in breast cancer and specifically consider whether expression in ductal carcinoma in… (More)
DOI: 10.3233/CBM-2009-0106

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