Higher expression and activity of metalloproteinases in human cervical carcinoma cell lines is associated with HPV presence.

@article{Cardeal2006HigherEA,
  title={Higher expression and activity of metalloproteinases in human cervical carcinoma cell lines is associated with HPV presence.},
  author={Laura Beatriz da Silva Cardeal and Carla Abdo Brohem and Tatiana Caroline Silveira Corr{\^e}a and Sheila Maria Brochado Winnischofer and F{\'a}bio Nakano and Enrique Boccardo and Luisa L. Villa and Mari Cleide Sogayar and Silvya Stuchi Maria-Engler},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={2006},
  volume={84 5},
  pages={713-9}
}
Matrix metalloproteinases (MMPs) MMP-2, MMP-9, and MT1-MMP are required for basement membrane degradation in cervical carcinoma. We evaluated the expression and activity of MMPs and their inhibitors RECK and TIMP-2 in 3 human invasive cervical carcinoma cell lines. Two HPV16-positive cell lines (SiHa and CaSki) and an HPV-negative cell line (C33A) were cultured either onto a type-I collagen gel, Matrigel, or plastic, to recreate their three-dimensional growth environment and evaluate the… CONTINUE READING

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MMP-9/RECK Imbalance: A Mechanism Associated with High-Grade Cervical Lesions and Genital Infection by Human Papillomavirus and Chlamydia trachomatis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2015
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Inflammation induced by human papillomavirus in cervical cancer and its implication in prevention.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation • 2014
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