Higher cathepsin B levels in plasma in Alzheimer's disease compared to healthy controls.

@article{Sundelf2010HigherCB,
  title={Higher cathepsin B levels in plasma in Alzheimer's disease compared to healthy controls.},
  author={Johan Sundel{\"o}f and Johan Sundstr{\"o}m and Oskar Hansson and Maria Eriksdotter-J{\"o}nhagen and Vilmantas Giedraitis and Anders Larsson and Malin Degerman-Gunnarsson and Martin Ingelsson and Lennart Minthon and K Blennow and Lena Kilander and Hans Basun and Lars Lannfelt},
  journal={Journal of Alzheimer's disease : JAD},
  year={2010},
  volume={22 4},
  pages={1223-30}
}
Cathepsin B is suggested to be involved in amyloid-β (Aβ) processing and Alzheimer's disease (AD). Studies of cathepsin B levels in plasma and cerebrospinal fluid (CSF) have not been previously performed. We examined cathepsin B levels in plasma and CSF samples in persons with AD, mild cognitive impairment (MCI), and healthy controls in order to test the hypothesis that cathepsin B levels can discriminate persons with AD or MCI from healthy controls. Cathepsin B, Cystatin C, Aβ1-40 and Aβ1-42… CONTINUE READING

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