High yielding synthesis of dehydroamino acid and dehydropeptide derivatives

@article{Ferreira1999HighYS,
  title={High yielding synthesis of dehydroamino acid and dehydropeptide derivatives},
  author={Paula M T Ferreira and Hern{\^a}ni L. S. Maia and Lu{\'i}s S Monteiro and Joana Sacramento},
  journal={Journal of The Chemical Society-perkin Transactions 1},
  year={1999},
  pages={3697-3703}
}
By using a 4-dimethylaminopyridine (DMAP) catalysed reaction of β-hydroxyamino acid derivatives with tert- butyl pyrocarbonate [(Boc)2O], dehydroamino acid derivatives are obtained in high yields. The same methodology applied to dipeptides with a β-hydroxyamino acid residue gives the corresponding dipeptides with a dehydroamino acid residue. 

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