High versus low-dose caffeine for apnea of prematurity: a randomized controlled trial

Abstract

The optimum caffeine dose in preterm infants has not been well investigated. We aimed to compare the efficacy and safety of high versus low-dose caffeine citrate on apnea of prematurity (AOP) and successful extubation of preterm infants from mechanical ventilation. We compared high-dose (loading 40 mg/kg/day and maintenance of 20 mg/kg/day) versus low-dose… (More)
DOI: 10.1007/s00431-015-2494-8

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@article{Mohammed2015HighVL, title={High versus low-dose caffeine for apnea of prematurity: a randomized controlled trial}, author={Sameh A Mohammed and Islam Nour and Abd Elazeez Shabaan and Basma Osama Shouman and H Abdel-Hady and Nehad Abdelsalam Nasef}, journal={European Journal of Pediatrics}, year={2015}, volume={174}, pages={949-956} }