High tryptophan diet reduces CA1 intraneuronal β-amyloid in the triple transgenic mouse model of Alzheimer's disease.

@article{Noristani2012HighTD,
  title={High tryptophan diet reduces CA1 intraneuronal β-amyloid in the triple transgenic mouse model of Alzheimer's disease.},
  author={Harun Najib Noristani and Alexei Verkhratsky and Jos{\'e} Julio Rodr{\'i}guez},
  journal={Aging cell},
  year={2012},
  volume={11 5},
  pages={810-22}
}
Alzheimer's disease (AD) is a progressive neurodegenerative disease that impairs mnesic functions. The histopathology of the disease is manifested by the accumulation of intracellular β-amyloid (Aβ) and subsequent formation of neuritic plaques as well as the presence neurofibrillary tangles in specific brain regions associated with learning and memory including the hippocampus. Here, we analysed the effect of chronic (1 month) food diets containing low (LTrP), normal (NTrP) and high tryptophan… CONTINUE READING
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