High titers of anti-human herpesvirus 8 antibodies in elderly males in an endemic population.

  title={High titers of anti-human herpesvirus 8 antibodies in elderly males in an endemic population.},
  author={Sabine Plancoulaine and Laurent Abel and Monique van Beveren and Antoine Gessain},
  journal={Journal of the National Cancer Institute},
  volume={94 17},
Human herpesvirus 8 (HHV8) is the etiologic agent of Kaposi's sarcoma (KS), a tumor occurring mainly among elderly men in its endemic and classical forms. The male-to-female ratio of KS in different endemic populations ranges from 3 : 1 to 15 : 1. We investigated the influence of age and gender on anti-HHV8 antibody titers among HHV8-seropositive subjects of an endemic population (1819 villagers with 874 men and 945 women) of African origin living in French Guiana. By using a specific… CONTINUE READING


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