High-throughput single strand conformation polymorphism mutation detection by automated capillary array electrophoresis: validation of the method.

@article{Andersen2003HighthroughputSS,
  title={High-throughput single strand conformation polymorphism mutation detection by automated capillary array electrophoresis: validation of the method.},
  author={Paal Skytt Andersen and Cathrine Jespersgaard and Jens Vuust and Michael Christiansen and Lars Allan Larsen},
  journal={Human mutation},
  year={2003},
  volume={21 2},
  pages={116-22}
}
Capillary array electrophoresis (CAE) is a novel technique, which allows for high throughput analysis of DNA fragments. When screening for mutations in whole populations or large patient groups it is necessary to have robust and well-characterized setups for high throughput analysis. For large-scale mutation screening, we have developed procedures for single strand conformation polymorphism (SSCP) assays using CAE (CAE-SSCP) whereby we may increase both the sensitivity and the throughput… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Polymorphisms in inflammation genes, tobacco smoke and furred pets and wheeze in children.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…