High-throughput screening of rare metabolically active tumor cells in pleural effusion and peripheral blood of lung cancer patients.

@article{Tang2017HighthroughputSO,
  title={High-throughput screening of rare metabolically active tumor cells in pleural effusion and peripheral blood of lung cancer patients.},
  author={Yin Tang and Zhuo Wang and Ziming Li and Jungwoo Kim and Yuliang Deng and Yan Li and James R. Heath and Wei Wei and Shun Lu and Qihui Shi},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2017},
  volume={114 10},
  pages={
          2544-2549
        }
}
Malignant pleural effusion (MPE), the presence of malignant cells in pleural fluid, is often the first sign of many cancers and occurs in patients with metastatic malignancies. Accurate detection of tumor cells in pleural fluid is crucial because the presence of MPE denotes an advanced stage of disease and directs a switch in clinical managements. Cytology, as a traditional diagnostic tool, has limited sensitivity especially when tumor cells are not abundant, and may be confounded by reactive… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 29 REFERENCES

Prognostic value of metabolic imaging in non-small cell lung cancers with neoplasic pleural effusion

  • B Duysinx
  • Nucl Med Commun
  • 2008
Highly Influential
7 Excerpts

Molecular analysis of circulating tumour cells-biology and biomarkers

  • MG Krebs
  • Nat Rev Clin Oncol 11(3):129–144
  • 2014
1 Excerpt