High-throughput screen detects calcium signaling dysfunction in typical sporadic autism spectrum disorder

@inproceedings{Schmunk2017HighthroughputSD,
  title={High-throughput screen detects calcium signaling dysfunction in typical sporadic autism spectrum disorder},
  author={Galina Schmunk and Rachel L. Nguyen and David L. Ferguson and K. Kantha Kumar and Ian Parker and John J. Gargus},
  booktitle={Scientific reports},
  year={2017}
}
Autism spectrum disorder (ASD) is a heterogeneous group of neurodevelopmental disorders without any defined uniting pathophysiology. Ca2+ signaling is emerging as a potential node in the genetic architecture of the disorder. We previously reported decreased inositol trisphosphate (IP3)-mediated Ca2+ release from the endoplasmic reticulum in several rare… CONTINUE READING