High-throughput quantification of the mechanical competence of murine femora--a highly automated approach for large-scale genetic studies.

Abstract

Animal models are widely used to gain insight into the role of genetics on bone structure and function. One of the main strategies to map the genes regulating specific traits is called quantitative trait loci (QTL) analysis, which generally requires a very large number of animals (often more than 1000) to reach statistical significance. QTL analysis for… (More)
DOI: 10.1016/j.bone.2013.02.015

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