High-throughput quantification of lysophosphatidylcholine by electrospray ionization tandem mass spectrometry.

@article{Liebisch2002HighthroughputQO,
  title={High-throughput quantification of lysophosphatidylcholine by electrospray ionization tandem mass spectrometry.},
  author={G. Liebisch and W. Drobnik and B. Lieser and G. Schmitz},
  journal={Clinical chemistry},
  year={2002},
  volume={48 12},
  pages={
          2217-24
        }
}
  • G. Liebisch, W. Drobnik, +1 author G. Schmitz
  • Published 2002
  • Chemistry, Medicine
  • Clinical chemistry
  • BACKGROUND Lysophosphatidylcholine (LPC) has been suggested to play a functional role in various diseases, including atherosclerosis, diabetes, and cancer mediated by LPC-specific G-protein-coupled receptors. Initial studies provided evidence for a potential use of LPC as diagnostic maker. However, existing methodologies are of limited value for a systematic evaluation of LPC species concentrations because of complicated, time-consuming procedures. We describe a methodology based on… CONTINUE READING

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