High-throughput quantification of lysophosphatidylcholine by electrospray ionization tandem mass spectrometry.

@article{Liebisch2002HighthroughputQO,
  title={High-throughput quantification of lysophosphatidylcholine by electrospray ionization tandem mass spectrometry.},
  author={Gerhard Liebisch and Wolfgang Drobnik and Bernd Lieser and Gerd Schmitz},
  journal={Clinical chemistry},
  year={2002},
  volume={48 12},
  pages={2217-24}
}
BACKGROUND Lysophosphatidylcholine (LPC) has been suggested to play a functional role in various diseases, including atherosclerosis, diabetes, and cancer mediated by LPC-specific G-protein-coupled receptors. Initial studies provided evidence for a potential use of LPC as diagnostic maker. However, existing methodologies are of limited value for a systematic evaluation of LPC species concentrations because of complicated, time-consuming procedures. We describe a methodology based on… CONTINUE READING
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Atherosclerosis. Nature 2000;407:233–41

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