High-throughput identification of novel conotoxins from the Chinese tubular cone snail (Conus betulinus) by multi-transcriptome sequencing

@article{Peng2016HighthroughputIO,
  title={High-throughput identification of novel conotoxins from the Chinese tubular cone snail (Conus betulinus) by multi-transcriptome sequencing},
  author={Chao Peng and Ge Yao and B. Gao and Chong-xu Fan and Chao Bian and Jintu Wang and Ying Cao and Bo Wen and Yabing Zhu and Zhiqiang Ruan and Xiaofei Zhao and Xinxin You and Jie Bai and Jia Li and Zhilong Lin and Shijie Zou and Xinhui Zhang and Ying Qiu and Jieming Chen and Steven L. Coon and Jia’an Yang and Jisheng Chen and Qiong Shi},
  journal={GigaScience},
  year={2016},
  volume={5}
}
BackgroundThe venom of predatory marine cone snails mainly contains a diverse array of unique bioactive peptides commonly referred to as conopeptides or conotoxins. These peptides have proven to be valuable pharmacological probes and potential drugs because of their high specificity and affinity to important ion channels, receptors and transporters of the nervous system. Most previous studies have focused specifically on the conopeptides from piscivorous and molluscivorous cone snails, but… Expand
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  • Frontiers in Marine Science
  • 2021
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