High-throughput functional screening for autophagy-related genes and identification of TM9SF1 as an autophagosome-inducing gene

@article{He2009HighthroughputFS,
  title={High-throughput functional screening for autophagy-related genes and identification of TM9SF1 as an autophagosome-inducing gene},
  author={Pengfei He and Z. Peng and Y. Luo and L. Wang and P. Yu and Weiwei Deng and Y. An and T. Shi and D. Ma},
  journal={Autophagy},
  year={2009},
  volume={5},
  pages={52 - 60}
}
  • Pengfei He, Z. Peng, +6 authors D. Ma
  • Published 2009
  • Biology, Medicine
  • Autophagy
  • Autophagy is a tightly regulated process responsible for the bulk degradation of most long-lived proteins and some organelles, which is associated with several forms of human disease including cancer, neurodegenerative disease, and cardiomyopathies. However, the molecular machinery involved in autophagy in mammalian cells remains poorly understood. Here, we describe a high-throughput, cell-based functional screening platform based on automated fluorescence microscopy system, that enable… CONTINUE READING
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