High-throughput co-encapsulation of self-ordered cell trains: cell pair interactions in microdroplets

@inproceedings{Lagus2013HighthroughputCO,
  title={High-throughput co-encapsulation of self-ordered cell trains: cell pair interactions in microdroplets},
  author={Todd P. Lagus and Jon F. Edd},
  year={2013}
}
Droplet microfluidics is a booming sub-field of microfluidics that adds the benefits of confinement, including signal accumulation and isolation, to cell analysis. However, controlling the number of cells per droplet has been limited to using Poisson (random) encapsulation for the highest throughputs. The Poisson probability of a droplet containing one and only one cell is limited to 36.8%, and the probability of pairing two distinct cell types in a droplet is limited to 13.5%. Combining… CONTINUE READING

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