High-throughput analysis of the impact of antibiotics on the human intestinal microbiota composition.

@article{Ladirat2013HighthroughputAO,
  title={High-throughput analysis of the impact of antibiotics on the human intestinal microbiota composition.},
  author={Stephanie E Ladirat and H A Schols and Arjen Nauta and Margriet H. C. Schoterman and Bart J. F. Keijser and Roy C. Montijn and Harry Gruppen and Frank H. J. Schuren},
  journal={Journal of microbiological methods},
  year={2013},
  volume={92 3},
  pages={387-97}
}
Antibiotic treatments can lead to a disruption of the human microbiota. In this in-vitro study, the impact of antibiotics on adult intestinal microbiota was monitored in a new high-throughput approach: a fermentation screening-platform was coupled with a phylogenetic microarray analysis (Intestinal-chip). Fecal inoculum from healthy adults was exposed in a fermentation screening-platform to seven widely-used antibiotics during 24h in-vitro fermentation and the microbiota composition was… CONTINUE READING
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Effect of antimicrobial agents on the ecological balance of human microflora

  • A. Sullivan
  • Lancet Infect. Dis
  • 2001
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