High-throughput analysis of Alzheimer's beta-amyloid aggregation using a microfluidic self-assembly of monomers.


The principal histopathological feature of Alzheimer's disease is the presence of beta-amyloid (Abeta) aggregates in the gray matter of the brain, and researchers believe that various environmental factors play significant roles in the conformational change and self-assembly of Abeta peptides. Therefore, discovering a rapid and convenient analytical method… (More)
DOI: 10.1021/ac802701z


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