High throughput DNA sequencing with a microfabricated 96-lane capillary array electrophoresis bioprocessor.

@article{Paegel2002HighTD,
  title={High throughput DNA sequencing with a microfabricated 96-lane capillary array electrophoresis bioprocessor.},
  author={Brian M Paegel and Charles A. Emrich and Gary J. Wedemayer and James R. Scherer and Richard A Mathies},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2002},
  volume={99 2},
  pages={
          574-9
        }
}
High throughput DNA sequencing has been performed by using a microfabricated 96-channel radial capillary array electrophoresis (microCAE) microchannel plate detected by a 4-color rotary confocal fluorescence scanner. The microchannel plate features a novel injector for uniform sieving matrix loading as well as high resolution, tapered turns that provide an effective separation length of 15.9 cm on a compact 150-mm diameter wafer. Expanded common buffer chambers for the cathode, anode, and waste… CONTINUE READING

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