High terminal deoxynucleotidyl transferase activity in acute myelogenous leukemia.

@article{Srivastava1976HighTD,
  title={High terminal deoxynucleotidyl transferase activity in acute myelogenous leukemia.},
  author={B. I. Sahai Srivastava and Sohaib Ahmed Khan and Edward S. Henderson},
  journal={Cancer research},
  year={1976},
  volume={36 10},
  pages={3847-50}
}
Although leukocytes from all 13 acute lymphoblastic leukemia patients examined had high terminal deoxynucleotidyl transferase (terminal transferase) activity (20 to 100 units/mg of cellular DNA, where 1 unit equals 1 nmole of nucleotide polymerized in 1 hr) and those from 21 acute myelocytic leukemia patients had low terminal transferase activity (0.2 to 2 units/mg of cellular DNA), the bone marrow and peripheral blood leukocytes from 2 patients with acute myelocytic leukemia, diagnosed on the… CONTINUE READING