High temperatures alter physiological properties of pyramidal cells and inhibitory interneurons in hippocampus

@inproceedings{Kim2012HighTA,
  title={High temperatures alter physiological properties of pyramidal cells and inhibitory interneurons in hippocampus},
  author={Jennifer A. Kim and Barry W. Connors},
  booktitle={Front. Cell. Neurosci.},
  year={2012}
}
Temperature has multiple effects on neurons, yet little is known about the effects of high temperature on the physiology of mammalian central neurons. Hyperthermia can influence behavior and cause febrile seizures. We studied the effects of acute hyperthermia on the immature hippocampus in vitro by recording from pyramidal neurons and inhibitory oriens-lacunosum moleculare (O-LM) interneurons (identified by green fluorescent protein (GFP) expression in the GIN mouse line). Warming to 41°C… CONTINUE READING

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