High telomerase activity is an independent prognostic indicator of poor outcome in colorectal cancer.

@article{Tatsumoto2000HighTA,
  title={High telomerase activity is an independent prognostic indicator of poor outcome in colorectal cancer.},
  author={Naokuni Tatsumoto and Eiso Hiyama and Yoshiko Murakami and Yasutaka Imamura and J W Shay and Yusuke Matsuura and Tadashi Yokoyama},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2000},
  volume={6 7},
  pages={2696-701}
}
Telomerase activity and altered telomere length have been extensively studied in many kinds of malignant tumors for clinical diagnostic and/or prognostic utilities. In the present study, we investigated telomerase activity and telomere length in colorectal cancers and noncancerous colonic mucosa specimens in 100 patients between 1991 and 1996. To determine whether the level of telomerase activity or telomere length is a prognostic indicator of patient outcome, we followed these patients more… CONTINUE READING

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