High-speed all-optical DNA local sequence alignment based on a three-dimensional artificial neural network.

Abstract

This paper presents an optical processing approach for exploring a large number of genome sequences. Specifically, we propose an optical correlator for global alignment and an extended moiré matching technique for local analysis of spatially coded DNA, whose output is fed to a novel three-dimensional artificial neural network for local DNA alignment. All… (More)
DOI: 10.1364/JOSAA.34.001173

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