High signal intensity in MR images of calcified brain tissue.


Calcified lesions of the brain occasionally appear bright on T1-weighted MR images. This report shows that particulate calcium can reduce T1 relaxation times by a surface relaxation mechanism. Calcium particles with greater surface area show greater T1 relaxivity. Reduced proton density and reduced T2 tend to diminish signal intensity, but reduced T1 increases signal intensity. Thus, for concentrations of calcium particulate of up to 30% by weight, the signal intensity on standard T1-weighted images increases but subsequently decreases.

Citations per Year

11,064 Citations

Semantic Scholar estimates that this publication has 11,064 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Henkelman1991HighSI, title={High signal intensity in MR images of calcified brain tissue.}, author={R. Mark Henkelman and John F. Watts and Walter Kucharczyk}, journal={Radiology}, year={1991}, volume={179 1}, pages={199-206} }