High serum levels of remnant lipoproteins predict ischemic stroke in patients with metabolic syndrome and mild carotid atherosclerosis.

@article{Nakamura2009HighSL,
  title={High serum levels of remnant lipoproteins predict ischemic stroke in patients with metabolic syndrome and mild carotid atherosclerosis.},
  author={Takamitsu Nakamura and Jun-ei Obata and Hajime Takano and Ken-ichi Kawabata and Keita Sano and Tsuyoshi Kobayashi and Daisuke Fujioka and Yukio Saito and Toshiaki Yano and Kiyotaka Kugiyama},
  journal={Atherosclerosis},
  year={2009},
  volume={202 1},
  pages={
          234-40
        }
}

High remnant lipoprotein predicts recurrent cardiovascular events on statin treatment after acute coronary syndrome.

TLDR
RLP-C is useful for risk assessment of secondary cardiovascular events in patients treated with statins after ACS and its addition to traditional risk factors enhanced net reclassification improvement (NRI) and integrated discrimination improvement (IDI).

Remnant Lipoproteins Are Residual Risk Factor for Future Cardiovascular Events in Patients With Stable Coronary Artery Disease and On-Statin Low-Density Lipoprotein Cholesterol Levels <70 mg/dL.

TLDR
RLP-C levels are a residual risk factor for future CVEs in patients with CAD and on-statin LDL-C <70 mg/dL and was a significant predictor of the primary endpoint after adjustment for known risk factors and lipid variables including triglycerides, and total apolipoprotein B.

High Levels of Remnant Lipoprotein Cholesterol Is a Risk Factor for Large Artery Atherosclerotic Stroke

TLDR
The association between high RLP-C levels and ischemic stroke, and in particular large artery atherosclerotic stroke, is found.

Prognostic Impact of Remnant-like Particle Cholesterol in Patients with Differing Glucose Metabolic Status: an Observational Cohort Study from China

TLDR
Higher R LP-C level is a significant and independent predictor of adverse prognosis in diabetic patients with NSTE-ACS who underwent PCI and the addition of RLP-C to the baseline model significantly enhanced the predictive value for adverse events both in the total and diabetic populations.

The longitudinal association of remnant cholesterol with cardiovascular outcomes in patients with diabetes and pre-diabetes

TLDR
It is demonstrated that higher RC levels were significantly associated with the worse prognosis in DM and pre-DM patients with CAD, suggesting that RC may be a target for patients with impaired glucose metabolism.

Association Between Changes in Lipid Profiles and Progression of Symptomatic Intracranial Atherosclerotic Stenosis: A Prospective Multicenter Study

TLDR
This is the first prospective multicenter study to demonstrate that high-density lipoprotein cholesterol elevation, along with remnant lipop protein cholesterol reduction and low apolipoprotein B/A-I, is associated with prevention of angiographic progression of symptomatic intracranial atherosclerotic stenosis.

Prognostic impact of estimated remnant-like particle cholesterol in patients with differing glycometabolic status: an observational cohort study from China

TLDR
High estimated RLP-C level is a significant predictor for recurrent adverse events in patients with diabetes and NSTE-ACS treated with PCI and the addition of estimated R LP-C to a baseline model including traditional risk factors enhanced the predictive performance both in total and diabetic populations.

References

SHOWING 1-10 OF 24 REFERENCES

Remnant lipoprotein levels in fasting serum predict coronary events in patients with coronary artery disease.

TLDR
Higher levels of remnant lipoproteins in fasting serum predict future coronary events in patients with CAD independently of other risk factors, according to multivariate Cox hazard analysis.

Blood Lipids and First-Ever Ischemic Stroke/Transient Ischemic Attack in the Bezafibrate Infarction Prevention (BIP) Registry: High Triglycerides Constitute an Independent Risk Factor

TLDR
High triglycerides constitute an independent risk factor for ischemic stroke/TIA across subgroups of age, sex, patient characteristics, and cholesterol fractions, whereas high %HDL was an independent protective factor among patients with CHD.

Association of remnant lipoprotein levels with impairment of endothelium-dependent vasomotor function in human coronary arteries.

TLDR
Remnant lipoprotein levels were independently associated with abnormal endothelium-dependent vasomotor function in large and resistance coronary arteries in humans, indicating that remnant lipoproteins may impair endothelial vasom motor function in human coronary arteries.

Echolucent Plaques Are Associated With High Risk of Ischemic Cerebrovascular Events in Carotid Stenosis: The Tromsø Study

TLDR
Subjects with echolucent atherosclerotic plaques have increased risk of ischemic cerebrovascular events independent of degree of stenosis and cardiovascular risk factors.

Ultrasonic evaluation of early carotid atherosclerosis.

TLDR
High-resolution real-time B-mode ultrasonography was performed to determine the extent of atherosclerosis, and it was quantified by using a scoring system to demonstrate the clinical usefulness of high-resolution B- modes for the evaluation of early carotid Atherosclerosis.

Ultrasound and lipoproteins as predictors of lipid-rich, rupture-prone plaques in the carotid artery.

  • M. Grønholdt
  • Medicine
    Arteriosclerosis, thrombosis, and vascular biology
  • 1999
TLDR
It appears that ultrasound B-mode imaging as well as lipoproteins presumably may predict dangerous and rupture-prone, lipid-rich plaques in the carotid arteries, thereby being potential diagnostic tools in the prevention of neurological events.