High serum androstenedione levels correlate with impaired memory in the surgically menopausal rat: a replication and new findings.

@article{Camp2012HighSA,
  title={High serum androstenedione levels correlate with impaired memory in the surgically menopausal rat: a replication and new findings.},
  author={Bryan W. Camp and Julia E. Gerson and Candy Wing S Tsang and Stephanie R. Villa and Jazmin I. Acosta and B Blair Braden and Ann N Hoffman and Cheryl D. Conrad and Heather A. Bimonte-Nelson},
  journal={The European journal of neuroscience},
  year={2012},
  volume={36 8},
  pages={3086-95}
}
After natural menopause in women, androstenedione becomes the primary hormone secreted by the residual follicle-depleted ovaries. In two independent studies, in rodents that had undergone ovarian follicular depletion, we found that higher endogenous serum androstenedione levels correlated with increased working memory errors. This led to the hypothesis that higher androstenedione levels impair memory. The current study directly tested this hypothesis, examining the cognitive effects of… CONTINUE READING
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Highly Influential
3 Excerpts

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