High serum IL-2 levels are predictive of prolonged survival in multiple myeloma.

@article{Cimino1990HighSI,
  title={High serum IL-2 levels are predictive of prolonged survival in multiple myeloma.},
  author={Guido Cimino and Giuseppe Avvisati and S. Amadori and Mariangela Cava and Diana Giannarelli and Gian Domenico Di Nucci and V Magliocca and Maria Teresa Petrucci and G P Poti and Cecilia Sgadari},
  journal={British journal of haematology},
  year={1990},
  volume={75 3},
  pages={373-7}
}
In this study we analysed serum IL-2 levels in 61 patients with multiple myeloma (MM). Patients serum IL-2 levels were significantly higher than normal controls. Moreover, higher serum IL-2 levels were associated with a prolonged actuarial survival. In particular, 87% of the MM patients with IL-2 greater the or equal to 10 U/ml are still alive at 5 years while only 13% of the remaining patients with IL-2 less than 10 U/ml are alive. The multivariate analysis confirmed these data indicating that… CONTINUE READING