High-sensitivity scanning calorimetric study of mixtures of cholesterol with dimyristoyl- and dipalmitoylphosphatidylcholines.

@article{Mabrey1978HighsensitivitySC,
  title={High-sensitivity scanning calorimetric study of mixtures of cholesterol with dimyristoyl- and dipalmitoylphosphatidylcholines.},
  author={S Mabrey and Pedro L. Mateo and Julian M. Sturtevant},
  journal={Biochemistry},
  year={1978},
  volume={17 12},
  pages={2464-8}
}
A highly sensitive and stable scanning microcalorimeter is employed in a reinvestigation of the effect of cholesterol on multilamellar suspensions of dimyristoylphosphatidylcholine (DMPC) and dipalmitoylphosphatidylcholine (DPPC). Below 20 mol % cholesterol the DPPC mixtures give heat-capacity curves each of which can be resolved into a narrow and a broad peak, suggesting the coexistence of two immiscible solid phases; above 20 mol % only the broad peak is observed and this disappears at about… CONTINUE READING

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