High sensitivity of free lambda and free kappa light chains for detection of intrathecal immunoglobulin synthesis in cerebrospinal fluid.

@article{Arneth2009HighSO,
  title={High sensitivity of free lambda and free kappa light chains for detection of intrathecal immunoglobulin synthesis in cerebrospinal fluid.},
  author={Borros M Arneth and F. Birklein},
  journal={Acta neurologica Scandinavica},
  year={2009},
  volume={119 1},
  pages={39-44}
}
BACKGROUND So far, an inflammation of the central nervous system (CNS) is diagnosed by immunoglobulin measurement in cerebrospinal fluid (CSF) and serum as well as by determination of the oligoclonal bands. With the free kappa and lambda light chains, new markers to diagnose intrathecal synthesis are available. METHODS In addition to routine diagnostic tests and the assessment of standard parameters, free immunoglobulin light chains were measured in the CSF of patients with neurological… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Intrathecal oligoclonal IgG synthesis in multiple sclerosis

Journal of Neuroimmunology • 2013
View 5 Excerpts
Highly Influenced

Oligoclonal free light chains in cerebrospinal fluid as markers of intrathecal inflammation. Comparison with oligoclonal IgG.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia • 2015

Similar Papers

Loading similar papers…