High-sensitivity detection of ATP using a localized surface plasmon resonance (LSPR) sensor and split aptamers.

@article{Park2015HighsensitivityDO,
  title={High-sensitivity detection of ATP using a localized surface plasmon resonance (LSPR) sensor and split aptamers.},
  author={Jin-ho Park and Ju-Young Byun and Won-Bo Shim and Seong U Kim and Min-Gon Kim},
  journal={Biosensors & bioelectronics},
  year={2015},
  volume={73},
  pages={26-31}
}
A highly sensitive localized surface plasmon resonance (LSPR) aptasensor for detection of adenosine triphosphate (ATP) has been developed. The sensor utilizes two split ATP aptamers, one (receptor fragment) being covalently attached to the surface of a gold nanorod (GNR) and the other labeled with a random DNA sequence and TAMRA dye (probe fragment). In the presence of both ATP and the probe fragment, a significant shift takes place in the wavelength of the LSPR band. This phenomenon is a… CONTINUE READING