High sensitivity, total body PET scanning using 3D data acquisition and reconstruction

@article{Cherry1991HighST,
  title={High sensitivity, total body PET scanning using 3D data acquisition and reconstruction},
  author={S. R. Cherry and Magnus Dahlbom and E C Hoffman},
  journal={Conference Record of the 1991 IEEE Nuclear Science Symposium and Medical Imaging Conference},
  year={1991},
  pages={1639-1643 vol.3}
}
Signal-to-noise ratio (S/N) gains of a factor of 2.4 have been demonstrated in phantom studies using a quasi-continuous 3-D data acquisition scheme and typical total body activity concentrations. The uniformity of S/N axially was also improved from 15% to 3%. The increase in sensitivity from 3-D data collection can potentially be used to reduce total body imaging time while maintaining S/N levels, and for obtaining good quality biodistribution images in animals using tracers with low specific… CONTINUE READING