High-risk syndrome for neuromyelitis optica: a descriptive and comparative study.

@article{Collongues2011HighriskSF,
  title={High-risk syndrome for neuromyelitis optica: a descriptive and comparative study.},
  author={Nicolas Collongues and Romain Marignier and H{\'e}l{\`e}ne Z{\'e}phir and Fr{\'e}d{\'e}ric Blanc and Sandra Vukusic and Olivier Outteryck and Marie Fleury and Aur{\'e}lie Ruet and Florent Borgel and Eric Thouvenot and Thibault Moreau and Gilles Defer and Nathalie Derache and Jean Pelletier and Bertrand Audoin and Marc Debouverie and Pierre Labauge and O Gout and William Camu and David Brassat and Bruno Brochet and Patrick Vermersch and Christian Confavreux and J{\'e}r{\^o}me de S{\'e}ze},
  journal={Multiple sclerosis},
  year={2011},
  volume={17 6},
  pages={720-4}
}
BACKGROUND Neuromyelitis optica (NMO) frequently begins with a monofocal episode of optic neuritis or myelitis. A concept named high-risk syndrome (HRS) for NMO has been proposed for patients with monofocal episodes and NMO-IgG antibodies. OBJECTIVE To describe HRS patients and compare them with NMO patients. METHODS We identified 30 patients with HRS: 18 with extensive myelitis (HRM) and 12 with optic neuritis (HRON), in a database pooling patients from 25 centres in France. Clinical… CONTINUE READING

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