High-risk human papillomavirus-positive lung cancer: molecular evidence for a pattern of pulmonary metastasis.

@article{Boerdonk2013HighriskHP,
  title={High-risk human papillomavirus-positive lung cancer: molecular evidence for a pattern of pulmonary metastasis.},
  author={Robert A A van Boerdonk and Johannes Marlene Daniels and Elisabeth Bloemena and Oscar Krijgsman and Renske D. M. Steenbergen and Ruud H. Brakenhoff and Katrien Gr{\"u}nberg and Bauke Ylstra and Chris J L M Meijer and Egbert F. Smit and Peter J. F. Snijders and Dani{\"e}lle A M Heideman},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2013},
  volume={8 6},
  pages={711-8}
}
INTRODUCTION Infection with high-risk types of human papillomavirus (hrHPV) is associated with cervical, anogenital, and oropharyngeal cancers. Since a causal contribution of hrHPV infection to lung cancer (LC) is still a matter of debate, a comprehensive study was performed to delineate hrHPV involvement in LC, using a Dutch study population. METHODS Archival tissue specimens from 223 patients (145 men, 78 women, median age 65 years, range 27-87 years), who presented with cancer in the lungs… CONTINUE READING