High resolution tumor targeting in living mice by means of multispectral optoacoustic tomography

@inproceedings{Buehler2012HighRT,
  title={High resolution tumor targeting in living mice by means of multispectral optoacoustic tomography},
  author={Andreas Buehler and Eva Herzog and Angelica Ale and Bradley D Smith and Vasilis Ntziachristos and Daniel Razansky},
  booktitle={EJNMMI Research},
  year={2012}
}
BackgroundTumor targeting is of high clinical and biological relevance, and major efforts have been made to develop molecular imaging technologies for visualization of the disease markers in tissue. Of particular interest is apoptosis which has a profound role within tumor development and has significant effect on cancer malignancy.MethodsHerein, we report on targeting of phosphatidylserine-exposing cells within live tumor allograft models using a synthetic near infrared zinc(II)-dipicolylamine… CONTINUE READING

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